Vitamin B3 CAS NO.98-92-0

• ProName: Nicotinamide
• CasNo: 98-92-0
• Molecular Formula: C6H6N2O
• Appearance: powder
• Application: It is an important raw material and in...
• DeliveryTime: prompt
• PackAge: according to the clients requirement
• Port: Shanghai
• ProductionCapacity: 1-1000 Metric Ton/Day
• Purity: 98%
• Storage: Store in dry, dark and ventilated plac...
• Transportation: by sea or by air
• LimitNum: 1 Gram
• Vitamin B2 are used to prevent vitamin B2 deficiency, such as angular cheilitis, chapped lips, glossitis, scrotum inflammation, conjunctivitis, seborrheic dermatitis, etc. It can also be used for total parenteral nutrition and insufficient intake. It also could be used in prevention of malnutrition, progressive weight loss and other diseases.

【Item name】Nicotinamide
【Other name】Niacinamide; Vitamin B3; 3-Pyridinecarboxamide; Nicotinamidum;
【CAS NO.】98-92-0
【Mol. Formula】C6H6N2O                                          
【Mol. Weight】122.1
【Assay】98.5~101.5%
【Appearance】White crystalline powder  
【Standard】Medicine grade, Food grade
【Packing】25kgs/drum (standard packing)
【Storage】Tight non-metallic container, protect from light

Nicotinamide is an amide of niacin, also is a member of the B group of vitamins, it is a water soluble vitamin, the product is white crystalline powder, odorless or nearly odorless, bitter in taste freely soluble in water or ethanol, dissolvable in glycerin. Niacin can be converted into niacinamide in vivo. Although both compounds have vitamin effects, niacinamide is less pharmacological and toxic than niacinic acid, and these effects occur during niacinic acid conversion.

Quality Standard

Item		Specifications
Appearance		White crystalline powder
Assay		98.5~101.5%
Identification	IR	Infrared absorption contrast pattern consistent
	UV	It meets the requirements in the chapter and the A245/262 ratio is 0.63~0.67
Readily carbonizable substances		Not deeper than the matching fluid A
Solubility		Freely soluble in water and in ethanol (95%)
Melting range		128.0℃~131.0℃
Loss on drying		≤0.5%
Residue on ignition		≤0.1%
Heavy metals (Pb)		≤20 ppm
- Mercury		≤0.1 ppm
- Lead		≤2.0 ppm
- Arsenic		≤1.0 ppm
- Cadmium		≤1.0 ppm
Total Plate Count		≤1000 CFU/g
Yeast & Mold		≤100 CFU/g
Coli		Negative
Salmonella		Negative

 

Function

Nicotinamide is easy to absorb oral and can be widely distributed in the body, the excess 

metabolites or prototype quickly expel from urine.Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism,maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role. 

Niacinamide is mainly used for prevention and treatment of pellagra stomatitis, glossitis, sick sinus syndrome, atrioventricular block and other problems.

In addition, nicotinamide has prevention and treatment of heart block, sinus node function and antifast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.

 

specification

appearance white crystalline powder

assay, % 98.5-101.5

melting range, ℃ 128-131
loss on drying ,% ≤0.5
residue on ignition, % ≤0.1
heavy metals,% ≤0.003

 

application

as a structured form of vitamins b, nicotinamide is an important component of coenzyme i and ii in the body of
both human and animals.

feed additives
* preventing the skin diseases and the diseases of alimentary canal
* promoting animal's growth, improving egg yield and hatching rates, ensuring good feathers.
* cure for mucosal inflammation and ulcers.
* preventing perosis of animals.

food additives and medicine
* preventing skin disease and diseases of alimentary canal, such as pellagra,dermatitis,black-tongue,vomiting and diarrhea etc.
* promoting substance and energy's metabolism in body, promoting body's growth in normal..
* cooperating with other medicine used to treat various mucosal inflammation and ulcers.
* strong effect on vasodilatation, improving supplying of blood, on cerebral thrombosis, coronary heart disease and hyperlipidemia .
* supplementing the lacking of niacin and nicotinamide due to long-term taking isoniazid and analogues.

daily cosmetics
in recent years, nicotinamide are widely used in cosmetics. 2% dosage of nicotinamide are used in the basic cream system of cosmetics, with white and anti-wrinkle effect. and used in shampoo & conditioner it has effect on stimulating hair follicle, improving follicle's blood circulation so as to prevent trichomadesis. in addition, because nicotinamide has the function on vasodilatation, it can also be used in the products for removing the dark circles around eyes.

 

packing

25kg/drum,or as per customer's requirement

storage & transport

stored in cool and airy place; away from fire and heat; handle with care; no breakage, avoid leakage

this is classified as a common good for transport.

 

 

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