Tofacitinib CAS NO.477600-75-2

• ProName:Manufacturer of Tofacitinib Citrate
• CasNo:477600-75-2
• Molecular Formula:C16H20N6O.C6H8O7
• Appearance:Off-white powder
• Application:API, Pharmaceutical raw material
• DeliveryTime:Prompt
• PackAge:1kg/bag, 10kg/drum
• Port:According to details
• Purity:≥99%
• Storage:Stored in a cool and dry well-closed c...
• Transportation:By air/by sea/by courier
• LimitNum:0
• Related Substances:Impurity 24 NMT 0.1% Any other singl...
• Residue on Ignition:Not more than 0.1%
• Heavy Metal:NMT 10ppm
• Valid Period:2 years

• Tofacitinib is suitable for adult patients with moderately to severely active rheumatoid arthritis (RA) who have insufficient efficacy or intolerance to methotrexate. It can be combined with methotrexate or other non-biological disease-modifying anti-rheumatic drugs. (DMARD) in combination.

 

 

Product Description        
  

• ProName:Manufacturer of Tofacitinib Citrate
• CasNo:477600-75-2
• Molecular Formula:C16H20N6O.C6H8O7
• Appearance:Off-white powder
• Application:API, Pharmaceutical raw material
• DeliveryTime:Prompt
• PackAge:1kg/bag, 10kg/drum
• Port:According to details
• Purity:≥99%
• Storage:Stored in a cool and dry well-closed c...
• Transportation:By air/by sea/by courier
• LimitNum:0
• Related Substances:Impurity 24 NMT 0.1% Any other singl...
• Residue on Ignition:Not more than 0.1%
• Heavy Metal:NMT 10ppm
• Valid Period:2 years

• Tofacitinib is suitable for adult patients with moderately to severely active rheumatoid arthritis (RA) who have insufficient efficacy or intolerance to methotrexate. It can be combined with methotrexate or other non-biological disease-modifying anti-rheumatic drugs. (DMARD) in combination.

Name: Tofacitinib

 

Synonyms: 3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

 

Molecular Structure

 

Molecular Formula: C16H20N6O

 

Molecular Weight: 312.37

 

CAS Registry Number: 477600-75-2

Chemical Name	tofacitinib
Synonyms	(3R,4R)-4-methyl-3-(methyl-1H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile;Tofacitinib;Tasocitinib;
CAS No.	477600-75-2
Molecular Formula	C16H20N6O
Molecular Weight	312.37000
PSA	88.91000
LogP	1.48268

Numbering system

UNII	87LA6FU830

Properties

Density	1.296g/cm3
Boiling Point	585.845ºC at 760 mmHg
Flash Point	308.108ºC
Refractive Index	1.646

 

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