Captopril CAS NO.62571-86-2

• ProName: Captopril Manufacturer/High quality/Be...
• CasNo: 62571-86-2
• Molecular Formula: C9H15NO3S
• Appearance: Crystalline Powder
• Application: It is an important raw material and in...
• DeliveryTime: prompt
• PackAge: according to the clients requirement
• Port: Shanghai
• ProductionCapacity: 1-100 Metric Ton/Month
• Purity: 99%
• Storage: Store in dry, dark and ventilated plac...
• Transportation: by sea or by air
• LimitNum: 1 Kilogram
• Grade: Industrial Grade

• Captopril is an angiotensin-converting enzyme inhibitor (ACE inhibitor or ACEI) that is used to treat high blood pressure and certain types of congestive heart failure.

 

Product Description        
  

• ProName: Captopril Manufacturer/High quality/Be...
• CasNo: 62571-86-2
• Molecular Formula: C9H15NO3S
• Appearance: Crystalline Powder
• Application: It is an important raw material and in...
• DeliveryTime: prompt
• PackAge: according to the clients requirement
• Port: Shanghai
• ProductionCapacity: 1-100 Metric Ton/Month
• Purity: 99%
• Storage: Store in dry, dark and ventilated plac...
• Transportation: by sea or by air
• LimitNum: 1 Kilogram
• Grade: Industrial Grade

 

product name	captopril
appearance	white or almost white crystalline powder
solubility	freely soluble in water,in methylene chloride and in methanol. it dissolves in dilute solutions of alkali hydroxides.
identification	ir spectrum conformod tothat of captopril crs
appearance of solutions	clear and colorless
melting range	between 104°c and 110°c
specific optical rotation	-125° to -130°
related substance ampa captopril disulfide single unknown impurity tctal unknown impurities	not more than 0.2% not more than 1.0% not more than 0.2% not more than 0.5%
heavy metals	not more than 0.003%
loss on drying	not more than 1.0%
sulphated ash	not more than 0.2%
assay	97.5%~102.0% calculated on anhydrous basis

 

Description

Captopril (rINN) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first ACE inhibitor developed and was considered a breakthrough both because of its novel mechanism of action and also because of the revolutionary development process. Captopril was discovered and developed at E. R. Squibb & Sons Pharmaceuticals based on concepts pioneered by Nobel Laureate John Vane and is now marketed by Bristol-Myers Squibb under the trade name Capoten.

Basic Info

Chemical Name	captopril
Synonyms	acepress;dilabar;capoten;Captopril;acediur;Expand
CAS No.	62571-86-2
Molecular Formula	C9H15NO3S
Molecular Weight	217.28500
PSA	96.41000
LogP	0.56580

Numbering system

MDL number

MFCD00168073

Properties

Appearance & Physical State	White to off-white crystalline power
Density	1.272 g/cm3
Boiling Point	427ºC at 760 mmHg
Melting Point	103-108ºC
Flash Point	212.1ºC
Refractive Index	-127.5 ° (C=1.7, EtOH)
Water Solubility	soluble
Stability	Stable. Incompatible with strong oxidizing agents.
Storage Condition	Store in a cool, dry place. Store in a tightly closed container.

Safety Info

RTECS	UY0550000
Safety Statements	S26-S37/39
HS Code	2933990090
WGK Germany	2
Risk Statements	R36/37/38
Hazard Codes	Xi
Hazard Declaration	H317; H361
Symbol	GHS07, GHS08
Signal Word	Warning
Caution Statement	P280

 

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