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Home > Products >  Adapalene

Adapalene CAS NO.106685-40-9

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Product Details

Keywords

  • Adapalene factory supplier
  • Adapalene powder
  • Adapalene

Quick Details

  • ProName: Adapalene
  • CasNo: 106685-40-9
  • Molecular Formula: C42H69N9O14S
  • Appearance: White powder
  • Application: Adapalene is a retinoic acid compound ...
  • DeliveryTime: 30days
  • PackAge: Barreled, aluminum foil bagged
  • Port: NINGBO/SHANGHAI
  • ProductionCapacity: 30 Metric Ton/Day
  • Purity: 99%
  • Transportation: Sea, air, and land transportation
  • LimitNum: 1 Kilogram

Superiority

  • ProName: Adapalene
  • CasNo: 106685-40-9
  • Molecular Formula: C28H28O3
  • Appearance: White powder
  • Application: The product is used for pharmaceutica...
  • DeliveryTime: Prompt delivery
  • PackAge: 1g/1kg/Al-foiled bag, 25kg/drum
  • Port: Any port in China
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99%
  • Storage: Store in well-closed container, protec...
  • Transportation: by air/by sea/by courier as per buyer’...
  • LimitNum: 1 Kilogram
  • Related Substances: Not more than 1.0%
  • Residue on Ignition: Not more than 0.5%
  • Heavy Metal: Not more than 20 ppm
  • Valid Period: 3 years
  • Identification: Meets the requirements
  • Adapalene is a retinoic acid compound that mainly binds to specific retinoic acid nuclear receptors; it reduces the formation of microacne by normalizing the differentiation of hair follicle epithelial cells. At the same time, this product can also alleviate the inflammatory reaction of acne.

Details

 

Product Description        
  

  • ProName: Adapalene
  • CasNo: 106685-40-9
  • Molecular Formula: C28H28O3
  • Appearance: White powder
  • Application: The product is used for pharmaceutica...
  • DeliveryTime: Prompt delivery
  • PackAge: 1g/1kg/Al-foiled bag, 25kg/drum
  • Port: Any port in China
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99%
  • Storage: Store in well-closed container, protec...
  • Transportation: by air/by sea/by courier as per buyer’...
  • LimitNum: 1 Kilogram
  • Related Substances: Not more than 1.0%
  • Residue on Ignition: Not more than 0.5%
  • Heavy Metal: Not more than 20 ppm
  • Valid Period: 3 years
  • Identification: Meets the requirements
  • Adapalene is a retinoic acid compound that mainly binds to specific retinoic acid nuclear receptors; it reduces the formation of microacne by normalizing the differentiation of hair follicle epithelial cells. At the same time, this product can also alleviate the inflammatory reaction of acne.

Items

Standard

Result

Appearance

White to almost white powder

White crystal

Identification

IR

Complies

Solubility

Practically insoluble m water and ethanol,sparingly soluble in tetrahydrofuran.

 Complies

Appearance of solution

Solution must clear and colour NMT BYof EP

 Complies

Heavy metals

≤20ppm

 Complies

Loss on drying

≤0.5%

0.16%

Sulfated ash

≤ 0.1 %

0.05%

 

Relative substance

Impurity A: ≤0.3%

Impurity D: ≤0.2%

Impurity C: ≤0.15%

Unknown impurity: ≤0.1% Total impurity: ≤0.5%

0.23%

0.09%

Not Detected

0.07%

0.39%

Residual solvent

Tetrahydrofuran:≤720 ppm Acetic acid: ≤5000 ppm Methanol: ≤3000 ppm Dichloromethane: ≤600 ppm N,N-dimethyl formamide; ≤880 ppm

630ppm

Not Detected

Not Detected

Not Detected

Not Detected

Assay(on dried basis)

98.0 -102.0%

99.4%

Conclusion

It complies to prescribed EP 7.0 standard

 

 

about our adapalene powder


adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. it is effective against acne conditions where comedones are predominant.

Items

 

Specification

 

Result

Appearance

White to off-white crystalline powder

Conform

Assay

98%-102%

99.6%

Loss on drying

≤0.5%

0.25%

Sulphated ash

≤0.1%

0.06%

Heavy metals

≤10ppm

<10ppm

Related substance

Impurity A≤0.3%

Impurity C≤0.25%

Impurity D≤0.1%

Max unknown impurity≤0.1%

Total impurities≤0.5%

Conform

 


 

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Our service:
1. Certificate Of Analysis (COA)

2. Material Safety Data Sheet (MSDS)

3. Route of synthesis (ROS)

4. Method of Aanlysis (MOA)

5. Nuclear Magnetic Resonance (NMR)

6. Any inquirie


 

 

Zhejiang Huili Pharmaceutical Co., Ltd. is a professional pharmaceutical company which provide service for large pharmaceutical and health care products companies, such as: Collon Group, Sinopharm Group, and so on.

We provide high quality medicial and health-care products like Active Pharmaceutical Ingredients, Empty Capsules, Packaging Machines, Health Care Products OEM services for hundreds of customers from dometic and aborad market.

Especially, we are professional phollow capsules manufacturer for more than 40 years, with 12 capsules semi-automatic production line, 8 billion annual production capacity, we own the inspection equipments imported from the United States and creat 100+ patents which make us provide satisfying service to our customers.

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