Ademetionine 1, 4-butanedisulfonate CAS NO.101020-79-5

Adenosine methionine is a physiologically active molecule commonly present in human tissues and body fluids. It participates in important biochemical reactions in the body as a precursor of methyl donors (transmethylation) and physiological thiol compounds (such as cysteine, taurine, glutathione, and coenzyme A).

In the liver, adenosylmethionine regulates the fluidity of liver cell membranes by methylation of plasma membrane phospholipids, and the synthesis of sulfide products during detoxification can be promoted through sulfur-containing reactions. These reactions help prevent intrahepatic cholestasis.

Product Name	Ademetionine 1,4-butanedisulfonate
CAS No.	101020-79-5
Molecular Formula	C23H41N6O17S5-
Molecular Weight	833.91
Usage	Treatment of intrahepatic cholestasis before and during cirrhosis. Treatment of intrahepatic cholestasis during pregnancy.

The multiple mechanisms of action of adenosylmethionine are mainly reflected in the following aspects:

1. Methylation: Improve the fluidity of liver cell membrane, enhance Na+- K+- ATPase activity, promote bile secretion and operation, and participate in neurotransmitter synthesis, which can improve patient mood.

2. Transsulfuryl: Generate endogenous detoxifiers such as cysteine, glutathione, taurine, etc., which exert detoxification and antioxidant effects, reducing liver cell damage.

3. Transpropylamine: Synthesize biogenic polyamines, participate in metabolism in the body, regulate liver cell regeneration and proliferation, and accelerate liver function repair.

Product Name: Adenylate 1,4-Butyldisulfonate

CAS number: 101020-79-5

Molecular formula: 2 (C15H23N6O5S). 2 (C4H10O6S2)

Appearance: White powder Application: It is an important raw material

Delivery time: Timely

Packaging: According to customer requirements

Port: Shanghai

Production capacity: 1-100 metric tons/month

Purity: 98%

Storage: Store in a dry, dark, and ventilated place

Transportation: sea or air freight

Limit quantity: 1 kilogram

Grade: Industrial grade

superior

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Reference COA

ITEMS	STANDARDS	RESULTS
Appearance	A white or almost white powder	White powder
Solubility	Freely soluble in water, practically insoluble in ethanol and in acetone.	Conforms
Identification	1.    The gas it produced can make wet potassium iodate test pater show blue.	Conforms
	2.    UV: it has absorption maximum at the 258nm
	3.    HPLC: the retention time of the principal peak in the chromatogram obtained with test solution is in accordance with that of the reference.
pH	2.1~2.5	2.4
Clarity and color of solution	Color: ≤Y3# or YG3#	Conforms
	A solution should be clear.
Isomers	(S,S-Isomer) ≥70%	74.00%
Related substances	Adenine≤0.4%	0.05%
	S-Adenosyl-L-Homocysteine≤0.4%	0.09%
	Methylthioadenosine≤2.0%	0.43%
	Decarboxylation adenosine methionine≤1.2%	1.00%
	The other unknown impurities≤1.0%	0.05%
	Total of impurities≤4.0%	1.80%
Water	≤6.0%	2.40%
Residual solvents	Ethyl acetate≤5000ppm	Conforms
Microbial limit tests	Bacteria≤1000cfu/g	Conforms
Bacterial endotoxins	≤0.438 EU/mg	Conforms
Content (dried basis)	Butanedisuphonic acid: 46.0~51.0%	47.20%
	Adenosine methionine: 48.0~53.0%	52.20%
	Total≥96.0%	99.40%
Conclusion	Conforms to enterprise standard

 

 

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